Gene Therapy
Datum: 11-03-2010 - 12-03-2010
Locatie: Conferentiehotel Kapellerput, Heeze
Omschrijving: Spring Symposium of the Dutch Society of Gene Therapy
March 11
12.00-13.00 Registration & Welcome
13.00-18.00 Educational sessions
• Katherine HighTranslational lessons of AAV-mediated gene transfer for hemophilia - of mice & men
• Chiara Bonini Gene editing in primary lymphocytes for cancer adoptive immunotherapy
• Annemieke Aartsma-RusProgress in therapeutic antisense appli¬cations for neuromuscular disorders
• Hidde Haisma Gene doping: fact or fiction?
19.00-21.00 DINNER table discussions
March 12
9.00-17.00 General meet
8.30-9.00 Registration & Welcome
9.00 Gerard Wagemaker: Opening
9.00-10.00 ZonMw Translationeel Gentherapeu¬tisch Onderzoek:
• Annemieke Aartsma-Rus: Antisense-mediated exon skipping for Duchenne Muscular Dystrophy
• Paula Montenegro Miranda: Assessment of liver transduction in hyperbilirubinemic Gunn rats using dif¬ferent adeno-associated virus serotypes via different administration routes and the effect of liver resection
• Henk Rozemuller: Lentiviral transduction of MPS1 (Hurler disease) bone marrow cells results in high production of alpha-L-iduronidase in vivo
• Merel Stok: Towards lentiviral gene therapy of Pompe disease
10.00-10.30 Elizabeth Vroom: Patient perspective on gene therapy clinical trials in the Netherlands: opportunities for the future
10.30-11.00 BREAK
11.00-12.00 Keynote speaker: Katherine High Gene therapy for genetic disease: brighter days ahead
12.00-12.20 Andreas Freidig: Beyond the bedside: development of a gene therapy medicinal product in the EU
12.20-12.40 Conclusions from dinner table discussions in short
12.40-14.00 LUNCH
13.30-14.00 Ledenvergadering
14.00-14.10 Ton Schumacher: Jury report and an¬nouncement winner Greiner Award 2009
14.10-14.30 Greiner Award winner
14.30-17.00 Presentations selected abstracts:
• Fatima Aerts-Kaya: Effects of immune modulation on the risk assessment of gene therapy
• Caroline Aalbers: Improvement of rAAV5 transductionefficiency in fibroblast-like synoviocytes by doxorubicin
• Maarten Holkers: Coordinated nicking of donor and chromosomal acceptor DNA stimulates homologous recombination in human cells
• Christie Vermeulen: Silencing a p53 inhibitor in cancer cells increases killing potency of oncolytic adenovirus
15.30-16.00 BREAK
• Victoria Marcu-Malina: Redirecting T-cells against cancer cells by transfer of broadly tumor reactive gamma-delta-T-cell receptors
• Mateusz Walczak: Heterologous compared to homologous prime-boost immunization results in higher CTL frequencies but not in higher anti-tumor responses
• Niek van Til: Lentiviral gene therapy of RAG1 severe combined immunodeficiency: risks and implications for treatment
• Marshall Huston: Lentiviral gene therapy of murine hematopoietic stem cells using codon optimised IL2RG: a comparison of multiple promoter elements and transplants conditions
17.00 DRINKS
17.00 Bestuursvergadering
Meer informatie: http://www.nvgt.nl
E-mailadres: nvgt@amc.nl
